William R. Wagner
Professor, Department of Surgery, Bioengineering, and Chemical
and Petroleum Engineering
100 Technology Drive, Suite 200
412-235-5138, 5110(fax)
wagnerwr@upmc.edu
http://www.mirm.pitt.edu/people/bios/Wagner1.html
William Wagner’s research generally focuses on cardiovascular
engineering, developing technologies that will aid in the
diagnosis and treatment of cardiovascular disease. A major
effort in his research group is to develop polymer, biomolecule
and cell processing methods that will create structures to
facilitate cardiovascular tissue regeneration. One particular
method involves electrospinning and electrospraying, where
electrical fields are employed to process polymers into scaffold
structures that have features on the sub-micron scale. When
scaffold structural features are controlled on this scale it is
possible to engineer spatial relationships and mechanical
properties that mimic native tissues in an advantageous manner.

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Electrospun biodegradable polyurethane with integrated
muscle cells. |